Caffeine may be the most popular legal addictive stimulant that is available to mankind. Besides coffee, tea, guarana and kola nut have excess amount of this xanthine alkaloid, which is actually acting as a psychoactive drug. In several plants, caffeine is an effective insect repellant, but this trimethylxanthine is deemed by the Food and Drug Administration as generally safe food substance. It is an antagonist of adenosine receptors. The effect of caffeine is individual and may more or less increase the ability to perform physical and mental labor. It reduces the effects of fatigue and may in long term help predominantly men reduce the risk of developing Parkinson’s disease. It has also been observed that caffeine has nootropic effects, furthermore, regular consumption of caffeine may significantly reduce the risk of heart diseases.

Chromium Polynicotinate is a product associated with medical food. It is used as a nutritional support in diabetes related conditions. Chromium polynicotinate is said to be nothing but an assimilated form of chromium. It is said to be the most effective type of chromium. It is absorbed by the body in its biologically active form. It is also crucial to the process of synthesis of fats, protein and cholesterol. Chromium polynicotinate if taken in monitored dosage can help stabilize blood sugar levels. This proves beneficial for people suffering from diabetes as well as hypoglycemia. Its main property is to produce insulin. Therefore, it helps in the metabolism of glucose. This type of chromium polynicotinate helps in the production of anabolic effects which have no side effects. On the other hand, they help in keeping the fat cells away from the muscle cells.

Cocoa Seed Extract, which is standardized for caffeine, tyramine, phenylethylamine and theobromine. Cocoa seed extract is thought to possibly help speed up the metabolism and provide feelings of fullness.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Garcinia Cambogia, which is used for the active ingredient, Hydrocitric Acid or HCA. It is extracted from the garcinia cambogia fruit, similar to an orange. It is commonly used as an appetite suppressant. Hydrocitric acid or HCA is a "lipogenesis inhibitor," which means that it slows down the production of fat from the metabolism of carbohydrates and proteins. This means that more calories are burned as energy and less are turned into stored fat. Studies on animals and humans have shown that HCA can suppress fat production and reduce appetite.

Ginger Root- Although used in cooking ginger is also used as a medicine. Medically it is a carminative, i.e. something that prevents the formation of intestinal gas, and as a stimulant, and is widely used for both colic and dyspepsia. Pregnant women are often recommended to eat ginger in the mornings in order to avoid morning sickness. It is generally safe to take although it is contraindicated in those taking Warfarin and also in those with gall stones as it can stimulate the liver’s production of bile. There is some evidence that ginger can ease arthritic pain and it is possible that it has blood thinning properties and may lower cholesterol levels

Green Tea Extract is of immense use to treat body ache, headaches and poor digestion. The green tea extract contains polyphenols to high levels and is an opulent source of antioxidant. It has the power of fighting free radicals more than vitamin E. the polyphenols present in green tea extract protect against respiratory and digestive infections. It blocks the carcinogens actions that promotes cancer and reduces the cholesterol levels. Green tea extract helps in metabolizing fat. The dieters can feel the weight loss without side effects and jitters. The green tea extract decreases the heart disease risk and also helps in preventing liver failure. The benefits of green tea extract are many, but as it contains caffeine, medical experts should be consulted prior to using it. Green tea extract also defends dental plaque. Green tea extracts prevents even liver transplant failure, but pregnant women should take green tea only after doctor consultation.

Guarana is not only a dietary supplement but also an energy booster as well as it has a high concentration of caffeine.

Hoodia Gordonii is an extract from the Hoodia plant of South West Africa. It is one of the fore runners in weight loss programs. Quenching thirst and providing energy are two of the numerous uses of the plant extract. The extract reduces gastric acid output in the stomach to a large extent, ranging from 40 – 60%. Aside from repressing hunger, Hoodia raises the overall energy levels in the body and will make a person feel completely healthy – both mentally and physically. Hoodia Gordonii is known to be extremely effective and does not have side effects such as dizziness, causing an increase of the heart beat or body temperature and sleeplessness. Hoodia Gordonii, however, should not be used during pregnancy and by nursing mothers.

Hordenine, which is found in many grassy plants and grains. Hordenine is related to tyramine and may stimulate the release of norepinephrine to produce a stimulant effect.

L-Tyrosine is a proteinogenic polar amino acid, deemed not essential because it can be synthesized by the human body. As a member of the amino acid group that is being used by cells to build proteins, this building block derived its name from the Greek word tyros, which means cheese, because it was discovered in the cheese protein casein. L-Tyrosine can be synthesized from phenylalanine and can be found in foods high on protein, like soy products, poultry, cheese, bananas, dairy products and several seeds, including the sesame seeds. The unique phenol functionality and the occurrence in proteins that belong to the signal transduction process, make this amino acid different. Tyrosine can be converted by tyrosine hydroxylase enzyme into levodopa, a psychoactive drug that is used, among other uses, for clinical treatment of Parkinson’s disease. It is also involved in the synthesis of dopamine, norepinephrine and epinephrine.

Octopamine is a biogenic substance which is containing an amine group, apparently related to noradrenaline, which is a catecholamine functioning as both, neurotransmitter and a hormone. Similar to norepinephrine, which is another name for noradrenaline, octopamine may act as a stress hormone, triggering increased heart rate, energy consumption and blood flow, even the blood pressure. One side effect of octopamine is apparently the release of fat from the adipocytes, which are the fat cells where excess energy is being stored. This side effect prompted the use of octopamine as a dietary supplement aimed at weight loss, but used in combination with other stimulants. Octopamine has been discovered in the middle of the twentieth century, but the use as a fat removal agent is very recent.

Pantothenic Acid is thought to reduce lactic acid accumulation in athletes, may improve oxygen utilization efficiency, and is believed to improve the body's ability to heal and possibly help in reducing acne

Synephrine, More commonly called "bitter orange" or Citrus Aurantium, which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Vinpocetine is a derivitate of the periwinkle plant and was developed in the latter part of the 1960’s. It can be used as a dietary supplement, which can be found online.

White Willow Bark possesses salicin that offers identical effect as aspirin and exhibits no side effects. This is the basis for aspirin synthesis. Chinese healers used it to control pain and the Native Americans also understood the value of it to get relief from headaches as well rheumatism. This also reduces fevers. The advantage of white willow bark is that it also helps in reducing weight and aids the diet goals. It is an anti-inflammatory and is analgesic, anti-rheumatic, fever reducer and gives relief from inflammatory pains such as rheumatism, carpal tunnel syndrome and arthritis. White willow bark is found in Asia and Europe. Taking one or two capsules at mealtimes is recommended. However, this dosage should not be exceeded. This does not exhibit significant side effects, but the tannins present in the white willow extract may result in stomach upset and may trouble if a person is allergic to aspirin.

Yerba Matte is believed to possess cancer-fighting properties and has shown to have a relaxing effect on muscle tissues and a stimulating effect on heart tissues.